| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42001175 | EBV | ENSG00000100316.16 | protein_coding | RPL3 | No | No | 6122 | P39023 Q96QL0 |
| TVIS10020781 | HBV | ENSG00000100316.16 | protein_coding | RPL3 | No | No | 6122 | P39023 Q96QL0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RPL3 |
|---|---|
| DrugBank ID | DB04865 |
| Drug Name | Omacetaxine mepesuccinate |
| Target ID | BE0003833 |
| UniProt ID | P39023 |
| Regulation Type | antagonist |
| PubMed IDs | 1730056; 2583270 |
| Citations | Tujebajeva RM, Graifer DM, Matasova NB, Fedorova OS, Odintsov VB, Ajtkhozhina NA, Karpova GG: Selective inhibition of the polypeptide chain elongation in eukaryotic cells. Biochim Biophys Acta. 1992 Jan 6;1129(2):177-82.@@Tujebajeva RM, Graifer DM, Karpova GG, Ajtkhozhina NA: Alkaloid homoharringtonine inhibits polypeptide chain elongation on human ribosomes on the step of peptide bond formation. FEBS Lett. 1989 Nov 6;257(2):254-6. |
| Groups | Approved; Investigational |
| Direct Classification | Cephalotaxus alkaloids |
| SMILES | [H][C@@]1(OC(=O)[C@@](O)(CCCC(C)(C)O)CC(=O)OC)C(OC)=C[C@]23CCCN2CCC2=CC4=C(OCO4)C=C2[C@]13[H] |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL46286 |
