Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10028124HBVENSG00000197632.9protein_codingSERPINB2NoNo5055P05120
TVIS10016458HBVENSG00000197632.9protein_codingSERPINB2NoNo5055P05120
TCGA Plot Options
Drug Information
GeneSERPINB2
DrugBank IDDB00031
Drug NameTenecteplase
Target IDBE0000969
UniProt IDP05120
Regulation Type
PubMed IDs17141398; 7958159; 3091604
CitationsVerkleij-Hagoort AC, Ursem NT, Hop WC, Geurts-Moespot A, Steegers EA, Sweep FC, Steegers-Theunissen RP: Complex congenital malformations and the impact of the plasminogen activator system and beta-hCG in amniotic fluid. Eur J Obstet Gynecol Reprod Biol. 2007 Nov;135(1):47-52. Epub 2006 Dec 1.@@Bremer HA, Brommer EJ, Wallenburg HC: Effects of labor and delivery on fibrinolysis. Eur J Obstet Gynecol Reprod Biol. 1994 Jun 30;55(3):163-8.@@Stump DC, Thienpont M, Collen D: Purification and characterization of a novel inhibitor of urokinase from human urine. Quantitation and preliminary characterization in plasma. J Biol Chem. 1986 Sep 25;261(27):12759-66.
GroupsApproved
Direct ClassificationPeptides
SMILES
PathwaysTenecteplase Action Pathway
PharmGKBPA164776757
ChEMBLCHEMBL2108791