| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10045815 | HBV | ENSG00000168065.16 | protein_coding | SLC22A11 | No | No | 55867 | Q9NSA0 |
| TVIS20016541 | HPV | ENSG00000168065.16 | protein_coding | SLC22A11 | No | No | 55867 | Q9NSA0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC22A11 |
|---|---|
| DrugBank ID | DB01032 |
| Drug Name | Probenecid |
| Target ID | BE0000879 |
| UniProt ID | Q9NSA0 |
| Regulation Type | inhibitor |
| PubMed IDs | 12023506; 12063169; 12130730; 15377641 |
| Citations | Enomoto A, Takeda M, Shimoda M, Narikawa S, Kobayashi Y, Kobayashi Y, Yamamoto T, Sekine T, Cha SH, Niwa T, Endou H: Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. J Pharmacol Exp Ther. 2002 Jun;301(3):797-802.@@Babu E, Takeda M, Narikawa S, Kobayashi Y, Enomoto A, Tojo A, Cha SH, Sekine T, Sakthisekaran D, Endou H: Role of human organic anion transporter 4 in the transport of ochratoxin A. Biochim Biophys Acta. 2002 Jun 12;1590(1-3):64-75.@@Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71.@@Hashimoto T, Narikawa S, Huang XL, Minematsu T, Usui T, Kamimura H, Endou H: Characterization of the renal tubular transport of zonampanel, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters. Drug Metab Dispos. 2004 Oct;32(10):1096-102. |
| Groups | Approved; Investigational |
| Direct Classification | Benzenesulfonamides |
| SMILES | CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O |
| Pathways | |
| PharmGKB | PA451106 |
| ChEMBL | CHEMBL897 |
