| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10026579 | HBV | ENSG00000197901.12 | protein_coding | SLC22A6 | No | No | 9356 | Q4U2R8 |
| TVIS10016229 | HBV | ENSG00000197901.12 | protein_coding | SLC22A6 | No | No | 9356 | Q4U2R8 |
| TVIS20035569 | HPV | ENSG00000197901.12 | protein_coding | SLC22A6 | No | No | 9356 | Q4U2R8 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC22A6 |
|---|---|
| DrugBank ID | DB01032 |
| Drug Name | Probenecid |
| Target ID | BE0001066 |
| UniProt ID | Q4U2R8 |
| Regulation Type | inhibitor |
| PubMed IDs | 11426832; 11669456; 12130730; 15377641; 11752352 |
| Citations | Takeda M, Narikawa S, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters. Eur J Pharmacol. 2001 May 11;419(2-3):113-20.@@Jung KY, Takeda M, Kim DK, Tojo A, Narikawa S, Yoo BS, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of ochratoxin A transport by human organic anion transporters. Life Sci. 2001 Sep 21;69(18):2123-35.@@Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71.@@Hashimoto T, Narikawa S, Huang XL, Minematsu T, Usui T, Kamimura H, Endou H: Characterization of the renal tubular transport of zonampanel, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters. Drug Metab Dispos. 2004 Oct;32(10):1096-102.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Benzenesulfonamides |
| SMILES | CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O |
| Pathways | |
| PharmGKB | PA451106 |
| ChEMBL | CHEMBL897 |
