| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10011487 | HBV | ENSG00000134538.3 | protein_coding | SLCO1B1 | No | No | 10599 | Q05CV5 Q9Y6L6 |
| TVIS10019738 | HBV | ENSG00000134538.3 | protein_coding | SLCO1B1 | No | No | 10599 | Q05CV5 Q9Y6L6 |
| TVIS10019683 | HBV | ENSG00000134538.3 | protein_coding | SLCO1B1 | No | No | 10599 | Q05CV5 Q9Y6L6 |
| TVIS10020373 | HBV | ENSG00000134538.3 | protein_coding | SLCO1B1 | No | No | 10599 | Q05CV5 Q9Y6L6 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | SLCO1B1 |
|---|---|
| DrugBank ID | DB01241 |
| Drug Name | Gemfibrozil |
| Target ID | BE0001004 |
| UniProt ID | Q9Y6L6 |
| Regulation Type | inhibitor |
| PubMed IDs | 19919292; 25941268 |
| Citations | Sharma P, Holmes VE, Elsby R, Lambert C, Surry D: Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions. Xenobiotica. 2010 Jan;40(1):24-37. doi: 10.3109/00498250903351013.@@Varma MV, Lin J, Bi YA, Kimoto E, Rodrigues AD: Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-beta-Glucuronide. Drug Metab Dispos. 2015 Jul;43(7):1108-18. doi: 10.1124/dmd.115.064303. Epub 2015 May 4. |
| Groups | Approved |
| Direct Classification | Phenol ethers |
| SMILES | CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1 |
| Pathways | |
| PharmGKB | PA449750 |
| ChEMBL | CHEMBL457 |
