| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30007102 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
| TVIS30012304 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
| TVIS30002720 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
| TVIS30016827 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
| TVIS30074963 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
| TVIS30081640 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
| TVIS30074966 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
| TVIS30043907 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
| TVIS30043908 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
| TVIS30043909 | HIV | ENSG00000168610.17 | protein_coding | STAT3 | Yes | No | 6774 | P40763 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | STAT3 |
|---|---|
| DrugBank ID | DB16630 |
| Drug Name | OPB-111077 |
| Target ID | BE0003462 |
| UniProt ID | P40763 |
| Regulation Type | inhibitor |
| PubMed IDs | 29511132 |
| Citations | Tolcher A, Flaherty K, Shapiro GI, Berlin J, Witzig T, Habermann T, Bullock A, Rock E, Elekes A, Lin C, Kostic D, Ohi N, Rasco D, Papadopoulos KP, Patnaik A, Smith L, Cote GM: A First-in-Human Phase I Study of OPB-111077, a Small-Molecule STAT3 and Oxidative Phosphorylation Inhibitor, in Patients with Advanced Cancers. Oncologist. 2018 Jun;23(6):658-e72. doi: 10.1634/theoncologist.2017-0325. Epub 2018 Mar 6. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
