| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30070060 | HIV | ENSG00000184428.13 | protein_coding | TOP1MT | No | No | 116447 | Q969P6 |
| TVIS30070061 | HIV | ENSG00000184428.13 | protein_coding | TOP1MT | No | No | 116447 | Q969P6 |
| TVIS30070062 | HIV | ENSG00000184428.13 | protein_coding | TOP1MT | No | No | 116447 | Q969P6 |
| TVIS30070063 | HIV | ENSG00000184428.13 | protein_coding | TOP1MT | No | No | 116447 | Q969P6 |
| TVIS30070064 | HIV | ENSG00000184428.13 | protein_coding | TOP1MT | No | No | 116447 | Q969P6 |
| TVIS44039999 | HTLV-1 | ENSG00000184428.13 | protein_coding | TOP1MT | No | No | 116447 | Q969P6 |
| TVIS44050650 | HTLV-1 | ENSG00000184428.13 | protein_coding | TOP1MT | No | No | 116447 | Q969P6 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TOP1MT |
|---|---|
| DrugBank ID | DB01030 |
| Drug Name | Topotecan |
| Target ID | BE0000091 |
| UniProt ID | Q969P6 |
| Regulation Type | inhibitor |
| PubMed IDs | 8390858 |
| Citations | Kosovsky MJ, Soslau G: Immunological identification of human platelet mitochondrial DNA topoisomerase I. Biochim Biophys Acta. 1993 Jun 24;1164(1):101-7. |
| Groups | Approved; Investigational |
| Direct Classification | Camptothecins |
| SMILES | CC[C@@]1(O)C(=O)OCC2=C1C=C1N(CC3=CC4=C(C=CC(O)=C4CN(C)C)N=C13)C2=O |
| Pathways | |
| PharmGKB | PA451729 |
| ChEMBL | CHEMBL84 |
