| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30064714 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
| TVIS30064715 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
| TVIS30064716 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
| TVIS30064717 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
| TVIS30064718 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
| TVIS30064719 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
| TVIS30064720 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
| TVIS30064721 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
| TVIS30064722 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
| TVIS30064723 | HIV | ENSG00000112062.13 | protein_coding | MAPK14 | No | No | 1432 | B4E0K5 L7RSM2 Q16539 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MAPK14 |
|---|---|
| DrugBank ID | DB06518 |
| Drug Name | R-1487 |
| Target ID | BE0001019 |
| UniProt ID | Q16539 |
| Regulation Type | |
| PubMed IDs | 21375264 |
| Citations | Goldstein DM, Soth M, Gabriel T, Dewdney N, Kuglstatter A, Arzeno H, Chen J, Bingenheimer W, Dalrymple SA, Dunn J, Farrell R, Frauchiger S, La Fargue J, Ghate M, Graves B, Hill RJ, Li F, Litman R, Loe B, McIntosh J, McWeeney D, Papp E, Park J, Reese HF, Roberts RT, Rotstein D, San Pablo B, Sarma K, Stahl M, Sung ML, Suttman RT, Sjogren EB, Tan Y, Trejo A, Welch M, Weller P, Wong BR, Zecic H: Discovery of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-p yrido[2,3-d]pyrimidin-7-one (pamapimod) and 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]py rimidin-7(8H)-one (R1487) as orally bioavailable and highly selective inhibitors of p38alpha mitogen-activated protein kinase. J Med Chem. 2011 Apr 14;54(7):2255-65. doi: 10.1021/jm101423y. Epub 2011 Mar 4. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | CN1C(=O)C(OC2=CC=C(F)C=C2F)=CC2=C1N=C(NC1CCOCC1)N=C2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1230122 |
