| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10029811 | HBV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
| TVIS10050262 | HBV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
| TVIS30008670 | HIV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
| TVIS30013262 | HIV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
| TVIS30013263 | HIV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
| TVIS30013264 | HIV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
| TVIS30013265 | HIV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
| TVIS30000925 | HIV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
| TVIS20007704 | HPV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
| TVIS20006010 | HPV | ENSG00000151623.15 | protein_coding | NR3C2 | No | No | 4306 | B0ZBF6 P08235 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NR3C2 |
|---|---|
| DrugBank ID | DB15114 |
| Drug Name | Vamorolone |
| Target ID | BE0000668 |
| UniProt ID | P08235 |
| Regulation Type | antagonist |
| PubMed IDs | 30745312 |
| Citations | Heier CR, Yu Q, Fiorillo AA, Tully CB, Tucker A, Mazala DA, Uaesoontrachoon K, Srinivassane S, Damsker JM, Hoffman EP, Nagaraju K, Spurney CF: Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy. Life Sci Alliance. 2019 Feb 11;2(1):e201800186. doi: 10.26508/lsa.201800186. Print 2019 Feb. |
| Groups | Approved; Investigational |
| Direct Classification | 21-hydroxysteroids |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)C3=CC[C@]2(C)[C@@]1(O)C(=O)CO |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2348780 |
