Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10032751HBVENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS20002957HPVENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS20031069HPVENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS20030899HPVENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS44021579HTLV-1ENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS44024241HTLV-1ENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS44014377HTLV-1ENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TVIS44029002HTLV-1ENSG00000011677.13protein_codingGABRA3NoNo2556P34903
TCGA Plot Options
Drug Information
GeneGABRA3
DrugBank IDDB04903
Drug NamePagoclone
Target IDBE0000523
UniProt IDP34903
Regulation Type
PubMed IDs16430927
CitationsAtack JR, Pike A, Marshall G, Stanley J, Lincoln R, Cook SM, Lewis RT, Blackaby WP, Goodacre SC, McKernan RM, Dawson GR, Wafford KA, Reynolds DS: The in vivo properties of pagoclone in rat are most likely mediated by 5'-hydroxy pagoclone. Neuropharmacology. 2006 May;50(6):677-89. Epub 2006 Jan 20.
GroupsInvestigational
Direct ClassificationNaphthyridines
SMILESCC(C)CCC(=O)CC1N(C(=O)C2=CC=CC=C12)C1=NC2=C(C=CC(Cl)=N2)C=C1
Pathways
PharmGKB
ChEMBLCHEMBL2104745