| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44038333 | HTLV-1 | ENSG00000082701.17 | protein_coding | GSK3B | Yes | No | 2932 | P49841 Q6FI27 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | GSK3B |
|---|---|
| DrugBank ID | DB14509 |
| Drug Name | Lithium carbonate |
| Target ID | BE0001065 |
| UniProt ID | P49841 |
| Regulation Type | |
| PubMed IDs | 16733521; 17628506; 19754466 |
| Citations | Borsotto M, Cavarec L, Bouillot M, Romey G, Macciardi F, Delaye A, Nasroune M, Bastucci M, Sambucy JL, Luan JJ, Charpagne A, Jouet V, Leger R, Lazdunski M, Cohen D, Chumakov I: PP2A-Bgamma subunit and KCNQ2 K+ channels in bipolar disorder. Pharmacogenomics J. 2007 Apr;7(2):123-32. Epub 2006 May 30.@@Adli M, Hollinde DL, Stamm T, Wiethoff K, Tsahuridu M, Kirchheiner J, Heinz A, Bauer M: Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta -50T/C single nucleotide polymorphism. Biol Psychiatry. 2007 Dec 1;62(11):1295-302. Epub 2007 Jul 12.@@O'Brien WT, Klein PS: Validating GSK3 as an in vivo target of lithium action. Biochem Soc Trans. 2009 Oct;37(Pt 5):1133-8. doi: 10.1042/BST0371133. |
| Groups | Approved |
| Direct Classification | Organic carbonic acids |
| SMILES | [Li+].[Li+].[O-]C([O-])=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1200826 |
