Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20000402HPVENSG00000164867.11protein_codingNOS3NoNo4846P29474
TVIS20061493HPVENSG00000164867.11protein_codingNOS3NoNo4846P29474
TCGA Plot Options
Drug Information
GeneNOS3
DrugBank IDDB03918
Drug Name6S-5,6,7,8-Tetrahydrobiopterin
Target IDBE0000263
UniProt IDP29474
Regulation Type
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct ClassificationBiopterins and derivatives
SMILES[H][C@@]1(CNC2=C(N1)C(=O)N=C(N)N2)[C@H](O)[C@@H](C)O
Pathways
PharmGKB
ChEMBL