VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS20020663 | HPV | ENSG00000172482.5 | protein_coding | AGXT | No | No | 189 | P21549 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | AGXT |
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DrugBank ID | DB00145 |
Drug Name | Glycine |
Target ID | BE0000316 |
UniProt ID | P21549 |
Regulation Type | substrate |
PubMed IDs | 16899523; 16990263; 17616291 |
Citations | Ricoult C, Echeverria LO, Cliquet JB, Limami AM: Characterization of alanine aminotransferase (AlaAT) multigene family and hypoxic response in young seedlings of the model legume Medicago truncatula. J Exp Bot. 2006;57(12):3079-89. Epub 2006 Aug 9.@@Han Q, Robinson H, Gao YG, Vogelaar N, Wilson SR, Rizzi M, Li J: Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase. J Biol Chem. 2006 Dec 1;281(48):37175-82. Epub 2006 Sep 21.@@Lu TC, Ko YZ, Huang HW, Hung YC, Lin YC, Peng WH: Analgesic and anti-inflammatory activities of aqueous extract from Glycine tomentella root in mice. J Ethnopharmacol. 2007 Aug 15;113(1):142-8. Epub 2007 May 31. |
Groups | Approved; Nutraceutical; Vet_approved |
Direct Classification | Alpha amino acids |
SMILES | NCC(O)=O |
Pathways | gamma-Glutamyltranspeptidase Deficiency; Lesch-Nyhan Syndrome (LNS); Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Molybdenum Cofactor Deficiency; AICA-Ribosiduria; Purine Nucleoside Phosphorylase Deficiency; gamma-Glutamyltransferase Deficiency; Hyperprolinemia Type II; Glutamate Metabolism; Adenine Phosphoribosyltransferase Deficiency (APRT); Mercaptopurine Action Pathway; 2-Hydroxyglutric Aciduria (D and L Form); L-Arginine:Glycine Amidinotransferase Deficiency; Hyperinsulinism-Hyperammonemia Syndrome; Congenital Bile Acid Synthesis Defect Type II; Porphyrin Metabolism; Prolidase Deficiency (PD); Glycine and Serine Metabolism; Carnitine Synthesis; Adenosine Deaminase Deficiency; Methionine Metabolism; Bile Acid Biosynthesis; Hyperprolinemia Type I; Cystathionine beta-Synthase Deficiency; Arginine and Proline Metabolism; 27-Hydroxylase Deficiency; Sarcosine Oncometabolite Pathway; Purine Metabolism; Gout or Kelley-Seegmiller Syndrome; Ammonia Recycling |
PharmGKB | PA449789 |
ChEMBL | CHEMBL773 |