| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44042872 | HTLV-1 | ENSG00000142192.22 | protein_coding | APP | No | No | 351 | A0A0A0MRG2 E9PG40 P05067 |
| TVIS44042875 | HTLV-1 | ENSG00000142192.22 | protein_coding | APP | No | No | 351 | A0A0A0MRG2 E9PG40 P05067 |
| TVIS44035325 | HTLV-1 | ENSG00000142192.22 | protein_coding | APP | No | No | 351 | A0A0A0MRG2 E9PG40 P05067 |
| TVIS44051683 | HTLV-1 | ENSG00000142192.22 | protein_coding | APP | No | No | 351 | A0A0A0MRG2 E9PG40 P05067 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | APP |
|---|---|
| DrugBank ID | DB01593 |
| Drug Name | Zinc |
| Target ID | BE0003392 |
| UniProt ID | P05067 |
| Regulation Type | cofactor |
| PubMed IDs | 24855651 |
| Citations | Mayer MC, Kaden D, Schauenburg L, Hancock MA, Voigt P, Roeser D, Barucker C, Than ME, Schaefer M, Multhaup G: Novel zinc-binding site in the E2 domain regulates amyloid precursor-like protein 1 (APLP1) oligomerization. J Biol Chem. 2014 Jul 4;289(27):19019-30. doi: 10.1074/jbc.M114.570382. Epub 2014 May 22. |
| Groups | Approved; Investigational |
| Direct Classification | Homogeneous transition metal compounds |
| SMILES | [Zn] |
| Pathways | Dihydropyrimidinase Deficiency; Rofecoxib Action Pathway; Losartan Action Pathway; AICA-Ribosiduria; Canavan Disease; Quinapril Action Pathway; Alkaptonuria; Eprosartan Action Pathway; gamma-Glutamyltransferase Deficiency; Pterine Biosynthesis; Sulindac Action Pathway; Rescinnamine Action Pathway; Piroxicam Action Pathway; Nabumetone Action Pathway; 2-Hydroxyglutric Aciduria (D and L Form); beta-Ureidopropionase Deficiency; Vitamin B6 Metabolism; Retinol Metabolism; Valsartan Action Pathway; Valdecoxib Action Pathway; Irbesartan Action Pathway; Adenosine Deaminase Deficiency; Hawkinsinuria; Methionine Metabolism; Ramipril Action Pathway; Benazepril Action Pathway; beta-Alanine Metabolism; Aspartate Metabolism; Diclofenac Action Pathway; Galactosemia |
| PharmGKB | PA451956 |
| ChEMBL | CHEMBL1201279 |
