| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009465 | HBV | ENSG00000130707.18 | protein_coding | ASS1 | No | No | 445 | P00966 Q5T6L4 |
| TVIS10036839 | HBV | ENSG00000130707.18 | protein_coding | ASS1 | No | No | 445 | P00966 Q5T6L4 |
| TVIS10062550 | HBV | ENSG00000130707.18 | protein_coding | ASS1 | No | No | 445 | P00966 Q5T6L4 |
| TVIS30088707 | HIV | ENSG00000130707.18 | protein_coding | ASS1 | No | No | 445 | P00966 Q5T6L4 |
| TVIS30072166 | HIV | ENSG00000130707.18 | protein_coding | ASS1 | No | No | 445 | P00966 Q5T6L4 |
| TVIS20065430 | HPV | ENSG00000130707.18 | protein_coding | ASS1 | No | No | 445 | P00966 Q5T6L4 |
| TVIS20034622 | HPV | ENSG00000130707.18 | protein_coding | ASS1 | No | No | 445 | P00966 Q5T6L4 |
| TVIS44022964 | HTLV-1 | ENSG00000130707.18 | protein_coding | ASS1 | No | No | 445 | P00966 Q5T6L4 |
| TVIS44040355 | HTLV-1 | ENSG00000130707.18 | protein_coding | ASS1 | No | No | 445 | P00966 Q5T6L4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ASS1 |
|---|---|
| DrugBank ID | DB00155 |
| Drug Name | Citrulline |
| Target ID | BE0000671 |
| UniProt ID | P00966 |
| Regulation Type | |
| PubMed IDs | 10353334; 10407171; 10944418; 11067741; 11072090 |
| Citations | Braissant O, Honegger P, Loup M, Iwase K, Takiguchi M, Bachmann C: Hyperammonemia: regulation of argininosuccinate synthetase and argininosuccinate lyase genes in aggregating cell cultures of fetal rat brain. Neurosci Lett. 1999 May 7;266(2):89-92.@@Braissant O, Gotoh T, Loup M, Mori M, Bachmann C: L-arginine uptake, the citrulline-NO cycle and arginase II in the rat brain: an in situ hybridization study. Brain Res Mol Brain Res. 1999 Jul 5;70(2):231-41.@@Keilhoff G, Reiser M, Stanarius A, Aoki E, Wolf G: Citrulline immunohistochemistry for demonstration of NOS activity in vivo and in vitro. Nitric Oxide. 2000 Aug;4(4):343-53.@@Zhang B, Cao GL, Domachowske J, Jackson MJ, Porasuphatana S, Rosen GM: Stable expression of varied levels of inducible nitric oxide synthase in primary cultures of endothelial cells. Anal Biochem. 2000 Nov 15;286(2):198-205.@@Zhang WY, Gotoh T, Oyadomari S, Mori M: Coinduction of inducible nitric oxide synthase and arginine recycling enzymes in cytokine-stimulated PC12 cells and high output production of nitric oxide. Brain Res Mol Brain Res. 2000 Nov 10;83(1-2):1-8. |
| Groups | Investigational; Nutraceutical |
| Direct Classification | L-alpha-amino acids |
| SMILES | N[C@@H](CCCNC(N)=O)C(O)=O |
| Pathways | Citrullinemia Type I; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Argininemia; Hyperornithinemia with Gyrate Atrophy (HOGA); Canavan Disease; Hypoacetylaspartia; Hyperprolinemia Type II; Argininosuccinic Aciduria; L-Arginine:Glycine Amidinotransferase Deficiency; Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Prolidase Deficiency (PD); Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Carbamoyl Phosphate Synthetase Deficiency; Ornithine Aminotransferase Deficiency (OAT Deficiency); Hyperprolinemia Type I; Aspartate Metabolism; Nitric Oxide Signaling Pathway; Arginine and Proline Metabolism; Ornithine Transcarbamylase Deficiency (OTC Deficiency); Prolinemia Type II; Urea Cycle |
| PharmGKB | PA164747225 |
| ChEMBL | CHEMBL444814 |
