| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42000890 | EBV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
| TVIS30013793 | HIV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
| TVIS30084602 | HIV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
| TVIS30077938 | HIV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
| TVIS30082163 | HIV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
| TVIS30072769 | HIV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
| TVIS20002068 | HPV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
| TVIS20006574 | HPV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
| TVIS20010570 | HPV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
| TVIS20006108 | HPV | ENSG00000148408.15 | protein_coding | CACNA1B | No | No | 774 | Q00975 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1B |
|---|---|
| DrugBank ID | DB00381 |
| Drug Name | Amlodipine |
| Target ID | BE0009351 |
| UniProt ID | Q00975 |
| Regulation Type | inhibitor |
| PubMed IDs | 20097194; 28611661; 9249249 |
| Citations | Miyashita Y, Furukawa T, Kamegaya E, Yoshii M, Nukada T: A region of N-type Ca(2+) channel critical for blockade by the dihydropyridine amlodipine. Eur J Pharmacol. 2010 Apr 25;632(1-3):14-22. doi: 10.1016/j.ejphar.2010.01.006. Epub 2010 Jan 22.@@Godfraind T: Discovery and Development of Calcium Channel Blockers. Front Pharmacol. 2017 May 29;8:286. doi: 10.3389/fphar.2017.00286. eCollection 2017.@@Furukawa T, Nukada T, Suzuki K, Fujita Y, Mori Y, Nishimura M, Yamanaka M: Voltage and pH dependent block of cloned N-type Ca2+ channels by amlodipine. Br J Pharmacol. 1997 Jul;121(6):1136-40. |
| Groups | Approved |
| Direct Classification | Dihydropyridinecarboxylic acids and derivatives |
| SMILES | CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC |
| Pathways | Amlodipine Action Pathway |
| PharmGKB | PA448388 |
| ChEMBL | CHEMBL1491 |
