Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10019340HBVENSG00000138109.11protein_codingCYP2C9NoNo1559P11712
S5RV20
TVIS10004620HBVENSG00000138109.11protein_codingCYP2C9NoNo1559P11712
S5RV20
TVIS10026382HBVENSG00000138109.11protein_codingCYP2C9NoNo1559P11712
S5RV20
TVIS10052680HBVENSG00000138109.11protein_codingCYP2C9NoNo1559P11712
S5RV20
TVIS10059518HBVENSG00000138109.11protein_codingCYP2C9NoNo1559P11712
S5RV20
TVIS30011464HIVENSG00000138109.11protein_codingCYP2C9NoNo1559P11712
S5RV20
TCGA Plot Options
Drug Information
GeneCYP2C9
DrugBank IDDB12319
Drug NameBenzbromarone
Target IDBE0002793
UniProt IDP11712
Regulation Typeinhibitor
PubMed IDs12814975; 15170332
CitationsLocuson CW 2nd, Wahlstrom JL, Rock DA, Rock DA, Jones JP: A new class of CYP2C9 inhibitors: probing 2C9 specificity with high-affinity benzbromarone derivatives. Drug Metab Dispos. 2003 Jul;31(7):967-71.@@Locuson CW 2nd, Rock DA, Jones JP: Quantitative binding models for CYP2C9 based on benzbromarone analogues. Biochemistry. 2004 Jun 8;43(22):6948-58.
GroupsInvestigational; Withdrawn
Direct ClassificationAryl-phenylketones
SMILESCCC1=C(C(=O)C2=CC(Br)=C(O)C(Br)=C2)C2=CC=CC=C2O1
Pathways
PharmGKB
ChEMBLCHEMBL388590