| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44027052 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
| TVIS44027053 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
| TVIS44027054 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
| TVIS44003695 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
| TVIS44003983 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
| TVIS44030487 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
| TVIS44006599 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
| TVIS44032977 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
| TVIS44017690 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
| TVIS44017691 | HTLV-1 | ENSG00000129521.15 | protein_coding | EGLN3 | No | No | 112399 | F8W1G2 Q3T1B0 Q9H6Z9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | EGLN3 |
|---|---|
| DrugBank ID | DB11682 |
| Drug Name | Daprodustat |
| Target ID | BE0002219 |
| UniProt ID | Q9H6Z9 |
| Regulation Type | inhibitor |
| PubMed IDs | 32880805; 33597868 |
| Citations | Dhillon S: Daprodustat: First Approval. Drugs. 2020 Sep;80(14):1491-1497. doi: 10.1007/s40265-020-01384-y.@@Zheng Q, Wang Y, Yang H, Sun L, Fu X, Wei R, Liu YN, Liu WJ: Efficacy and Safety of Daprodustat for Anemia Therapy in Chronic Kidney Disease Patients: A Systematic Review and Meta-Analysis. Front Pharmacol. 2021 Jan 12;11:573645. doi: 10.3389/fphar.2020.573645. eCollection 2020. |
| Groups | Approved; Investigational |
| Direct Classification | N-acyl-alpha amino acids |
| SMILES | OC(=O)CNC(=O)C1C(=O)N(C2CCCCC2)C(=O)N(C2CCCCC2)C1=O |
| Pathways | |
| PharmGKB | PA166280581 |
| ChEMBL | CHEMBL3544988 |
