VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS10016557 | HBV | ENSG00000160867.15 | protein_coding | FGFR4 | Yes | No | 2264 | J3KPQ0 P22455 |
TVIS10030492 | HBV | ENSG00000160867.15 | protein_coding | FGFR4 | Yes | No | 2264 | J3KPQ0 P22455 |
TVIS30079903 | HIV | ENSG00000160867.15 | protein_coding | FGFR4 | Yes | No | 2264 | J3KPQ0 P22455 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | FGFR4 |
---|---|
DrugBank ID | DB09078 |
Drug Name | Lenvatinib |
Target ID | BE0001203 |
UniProt ID | P22455 |
Regulation Type | inhibitor |
PubMed IDs | 17943726 |
Citations | Matsui J, Yamamoto Y, Funahashi Y, Tsuruoka A, Watanabe T, Wakabayashi T, Uenaka T, Asada M: E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition. Int J Cancer. 2008 Feb 1;122(3):664-71. |
Groups | Approved; Investigational |
Direct Classification | Quinoline carboxamides |
SMILES | COC1=C(C=C2C(OC3=CC=C(NC(=O)NC4CC4)C(Cl)=C3)=CC=NC2=C1)C(N)=O |
Pathways | |
PharmGKB | PA166153472 |
ChEMBL | CHEMBL1289601 |