Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10016557HBVENSG00000160867.15protein_codingFGFR4YesNo2264J3KPQ0
P22455
TVIS10030492HBVENSG00000160867.15protein_codingFGFR4YesNo2264J3KPQ0
P22455
TVIS30079903HIVENSG00000160867.15protein_codingFGFR4YesNo2264J3KPQ0
P22455
TCGA Plot Options
Drug Information
GeneFGFR4
DrugBank IDDB09078
Drug NameLenvatinib
Target IDBE0001203
UniProt IDP22455
Regulation Typeinhibitor
PubMed IDs17943726
CitationsMatsui J, Yamamoto Y, Funahashi Y, Tsuruoka A, Watanabe T, Wakabayashi T, Uenaka T, Asada M: E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition. Int J Cancer. 2008 Feb 1;122(3):664-71.
GroupsApproved; Investigational
Direct ClassificationQuinoline carboxamides
SMILESCOC1=C(C=C2C(OC3=CC=C(NC(=O)NC4CC4)C(Cl)=C3)=CC=NC2=C1)C(N)=O
Pathways
PharmGKBPA166153472
ChEMBLCHEMBL1289601