| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20067481 | HPV | ENSG00000170820.12 | protein_coding | FSHR | No | No | 2492 | A0A1D5RMN4 P23945 |
| TVIS20033232 | HPV | ENSG00000170820.12 | protein_coding | FSHR | No | No | 2492 | A0A1D5RMN4 P23945 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FSHR |
|---|---|
| DrugBank ID | DB00094 |
| Drug Name | Urofollitropin |
| Target ID | BE0000387 |
| UniProt ID | P23945 |
| Regulation Type | agonist |
| PubMed IDs | 11299519; 7755615; 2108722; 8319832; 8070368; 11752352 |
| Citations | Layman LC: Mutations in the follicle-stimulating hormone-beta (FSH beta) and FSH receptor genes in mice and humans. Semin Reprod Med. 2000;18(1):5-10.@@Leng N, Dattatreyamurty B, Reichert LE Jr: Identification of amino acid residues 300-315 of the rat FSH receptor as a hormone binding domain: evidence for its interaction with specific regions of FSH beta-subunit. Biochem Biophys Res Commun. 1995 May 16;210(2):392-9.@@Santa Coloma TA, Dattatreyamurty B, Reichert LE Jr: A synthetic peptide corresponding to human FSH beta-subunit 33-53 binds to FSH receptor, stimulates basal estradiol biosynthesis, and is a partial antagonist of FSH. Biochemistry. 1990 Feb 6;29(5):1194-200.@@Dattatreyamurty B, Reichert LE Jr: Identification of regions of the follitropin (FSH) beta-subunit that interact with the N-terminus region (residues 9-30) of the FSH receptor. Mol Cell Endocrinol. 1993 May;93(1):39-46.@@Lindau-Shepard B, Roth KE, Dias JA: Identification of amino acids in the C-terminal region of human follicle-stimulating hormone (FSH) beta-subunit involved in binding to human FSH receptor. Endocrinology. 1994 Sep;135(3):1235-40.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Vet_approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA451835 |
| ChEMBL | CHEMBL1201520 |
