| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20052584 | HPV | ENSG00000166123.14 | protein_coding | GPT2 | No | No | 84706 | Q8TD30 |
| TVIS44021026 | HTLV-1 | ENSG00000166123.14 | protein_coding | GPT2 | No | No | 84706 | Q8TD30 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GPT2 |
|---|---|
| DrugBank ID | DB00160 |
| Drug Name | Alanine |
| Target ID | BE0002166 |
| UniProt ID | Q8TD30 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 11863375; 15122758; 16495081 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Yang RZ, Blaileanu G, Hansen BC, Shuldiner AR, Gong DW: cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase. Genomics. 2002 Mar;79(3):445-50.@@Jadhao SB, Yang RZ, Lin Q, Hu H, Anania FA, Shuldiner AR, Gong DW: Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver. Hepatology. 2004 May;39(5):1297-302.@@Rajamohan F, Nelms L, Joslin DL, Lu B, Reagan WJ, Lawton M: cDNA cloning, expression, purification, distribution, and characterization of biologically active canine alanine aminotransferase-1. Protein Expr Purif. 2006 Jul;48(1):81-9. Epub 2006 Jan 30. |
| Groups | Nutraceutical |
| Direct Classification | Alanine and derivatives |
| SMILES | C[C@H](N)C(O)=O |
| Pathways | gamma-Glutamyltranspeptidase Deficiency; Clomocycline Action Pathway; Josamycin Action Pathway; Gentamicin Action Pathway; Kanamycin Action Pathway; 5-Oxoprolinuria; Azithromycin Action Pathway; Glutamate Metabolism; Clindamycin Action Pathway; Clarithromycin Action Pathway; Argininosuccinic Aciduria; Hyperinsulinism-Hyperammonemia Syndrome; Tryptophan Metabolism; Alanine Metabolism; Glutaminolysis and Cancer; Glycine and Serine Metabolism; Troleandomycin Action Pathway; Dimethylglycine Dehydrogenase Deficiency; Selenoamino Acid Metabolism; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Erythromycin Action Pathway; Netilmicin Action Pathway; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Glutathione Metabolism; Neomycin Action Pathway; Roxithromycin Action Pathway; Arbekacin Action Pathway; Streptomycin Action Pathway |
| PharmGKB | PA448055 |
| ChEMBL | CHEMBL279597 |
