| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10019602 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
| TVIS10018253 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
| TVIS10005829 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
| TVIS10005828 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
| TVIS10033234 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
| TVIS10036190 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
| TVIS10019936 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
| TVIS10020135 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
| TVIS10042400 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
| TVIS10062547 | HBV | ENSG00000198785.7 | protein_coding | GRIN3A | No | No | 116443 | Q8TCU5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRIN3A |
|---|---|
| DrugBank ID | DB00514 |
| Drug Name | Dextromethorphan |
| Target ID | BE0000641 |
| UniProt ID | Q8TCU5 |
| Regulation Type | antagonist |
| PubMed IDs | 17139284; 17016423; 10064839; 2897648; 18812887 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Chou YC, Liao JF, Chang WY, Lin MF, Chen CF: Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextromethorphan and dextrorphan. Brain Res. 1999 Mar 13;821(2):516-9.@@Wong BY, Coulter DA, Choi DW, Prince DA: Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices. Neurosci Lett. 1988 Feb 29;85(2):261-6.@@Kamel IR, Wendling WW, Chen D, Wendling KS, Harakal C, Carlsson C: N-methyl-D-aspartate (NMDA) antagonists--S(+)-ketamine, dextrorphan, and dextromethorphan--act as calcium antagonists on bovine cerebral arteries. J Neurosurg Anesthesiol. 2008 Oct;20(4):241-8. doi: 10.1097/ANA.0b013e31817f523f. |
| Groups | Approved |
| Direct Classification | Morphinans |
| SMILES | [H][C@]12CCCC[C@]11CCN(C)[C@H]2CC2=C1C=C(OC)C=C2 |
| Pathways | |
| PharmGKB | PA449273 |
| ChEMBL | CHEMBL52440 |
