| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20019218 | HPV | ENSG00000137252.10 | protein_coding | HCRTR2 | No | No | 3062 | O43614 S4X0W3 |
| TVIS20061206 | HPV | ENSG00000137252.10 | protein_coding | HCRTR2 | No | No | 3062 | O43614 S4X0W3 |
| TVIS44033822 | HTLV-1 | ENSG00000137252.10 | protein_coding | HCRTR2 | No | No | 3062 | O43614 S4X0W3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
▼
| Gene | HCRTR2 |
|---|---|
| DrugBank ID | DB15031 |
| Drug Name | Daridorexant |
| Target ID | BE0005865 |
| UniProt ID | O43614 |
| Regulation Type | antagonist |
| PubMed IDs | 34415378 |
| Citations | Roch C, Bergamini G, Steiner MA, Clozel M: Nonclinical pharmacology of daridorexant: a new dual orexin receptor antagonist for the treatment of insomnia. Psychopharmacology (Berl). 2021 Oct;238(10):2693-2708. doi: 10.1007/s00213-021-05954-0. Epub 2021 Aug 20. |
| Groups | Approved |
| Direct Classification | |
| SMILES | COC1=CC(C(=O)N2CCC[C@@]2(C)C2=NC3=C(N2)C=CC(Cl)=C3C)=C(C=C1)N1N=CC=N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL4297590 |
