Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30012527HIVENSG00000090339.9protein_codingICAM1NoNo3383P05362
TVIS30012528HIVENSG00000090339.9protein_codingICAM1NoNo3383P05362
TVIS44007915HTLV-1ENSG00000090339.9protein_codingICAM1NoNo3383P05362
TCGA Plot Options
Drug Information
GeneICAM1
DrugBank IDDB12598
Drug NameNafamostat
Target IDBE0001085
UniProt IDP05362
Regulation Typeinhibitor
PubMed IDs25954127
CitationsKang MW, Song HJ, Kang SK, Kim Y, Jung SB, Jee S, Moon JY, Suh KS, Lee SD, Jeon BH, Kim CS: Nafamostat Mesilate Inhibits TNF-alpha-Induced Vascular Endothelial Cell Dysfunction by Inhibiting Reactive Oxygen Species Production. Korean J Physiol Pharmacol. 2015 May;19(3):229-34. doi: 10.4196/kjpp.2015.19.3.229. Epub 2015 Apr 30.
GroupsInvestigational
Direct ClassificationGuanidinobenzoic acids and derivatives
SMILESNC(=N)NC1=CC=C(C=C1)C(=O)OC1=CC2=C(C=C1)C=C(C=C2)C(N)=N
Pathways
PharmGKB
ChEMBLCHEMBL273264