| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10015661 | HBV | ENSG00000113302.6 | protein_coding | IL12B | No | No | 3593 | P29460 |
| TVIS10030453 | HBV | ENSG00000113302.6 | protein_coding | IL12B | No | No | 3593 | P29460 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IL12B |
|---|---|
| DrugBank ID | DB05679 |
| Drug Name | Ustekinumab |
| Target ID | BE0000981 |
| UniProt ID | P29460 |
| Regulation Type | inhibitor |
| PubMed IDs | 17761156; 17979029 |
| Citations | Reddy M, Davis C, Wong J, Marsters P, Pendley C, Prabhakar U: Modulation of CLA, IL-12R, CD40L, and IL-2Ralpha expression and inhibition of IL-12- and IL-23-induced cytokine secretion by CNTO 1275. Cell Immunol. 2007 May;247(1):1-11. Epub 2007 Aug 29.@@Wittig BM: Drug evaluation: CNTO-1275, a mAb against IL-12/IL-23p40 for the potential treatment of inflammatory diseases. Curr Opin Investig Drugs. 2007 Nov;8(11):947-54. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1201835 |
