| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10060311 | HBV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS30087023 | HIV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS30074133 | HIV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20007384 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20007385 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20004195 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20065658 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20043075 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20024956 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20034877 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | INSR |
|---|---|
| DrugBank ID | DB00047 |
| Drug Name | Insulin glargine |
| Target ID | BE0000033 |
| UniProt ID | P06213 |
| Regulation Type | agonist |
| PubMed IDs | 11752352; 17922476; 20424816; 18585815 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Le Roith D: Insulin glargine and receptor-mediated signalling: clinical implications in treating type 2 diabetes. Diabetes Metab Res Rev. 2007 Nov;23(8):593-9.@@Sciacca L, Cassarino MF, Genua M, Pandini G, Le Moli R, Squatrito S, Vigneri R: Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling. Diabetologia. 2010 Aug;53(8):1743-53. doi: 10.1007/s00125-010-1760-6. Epub 2010 Apr 28.@@Wada T, Azegami M, Sugiyama M, Tsuneki H, Sasaoka T: Characteristics of signalling properties mediated by long-acting insulin analogue glargine and detemir in target cells of insulin. Diabetes Res Clin Pract. 2008 Sep;81(3):269-77. doi: 10.1016/j.diabres.2008.05.007. Epub 2008 Jun 27. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA449992 |
| ChEMBL | CHEMBL1201497 |
