| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30006157 | HIV | ENSG00000139626.16 | protein_coding | ITGB7 | No | No | 3695 | P26010 |
| TVIS30011730 | HIV | ENSG00000139626.16 | protein_coding | ITGB7 | No | No | 3695 | P26010 |
| TVIS30021227 | HIV | ENSG00000139626.16 | protein_coding | ITGB7 | No | No | 3695 | P26010 |
| TVIS20020554 | HPV | ENSG00000139626.16 | protein_coding | ITGB7 | No | No | 3695 | P26010 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ITGB7 |
|---|---|
| DrugBank ID | DB12189 |
| Drug Name | Etrolizumab |
| Target ID | BE0003414 |
| UniProt ID | P26010 |
| Regulation Type | binder |
| PubMed IDs | 21232034; 30774593 |
| Citations | Stefanich EG, Danilenko DM, Wang H, O'Byrne S, Erickson R, Gelzleichter T, Hiraragi H, Chiu H, Ivelja S, Jeet S, Gadkari S, Hwang O, Fuh F, Looney C, Howell K, Albert V, Balazs M, Refino C, Fong S, Iyer S, Williams M: A humanized monoclonal antibody targeting the beta7 integrin selectively blocks intestinal homing of T lymphocytes. Br J Pharmacol. 2011 Apr;162(8):1855-70. doi: 10.1111/j.1476-5381.2011.01205.x.@@Lichnog C, Klabunde S, Becker E, Fuh F, Tripal P, Atreya R, Klenske E, Erickson R, Chiu H, Reed C, Chung S, Neufert C, Atreya I, McBride J, Neurath MF, Zundler S: Cellular Mechanisms of Etrolizumab Treatment in Inflammatory Bowel Disease. Front Pharmacol. 2019 Feb 1;10:39. doi: 10.3389/fphar.2019.00039. eCollection 2019. |
| Groups | Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
