| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44029873 | HTLV-1 | ENSG00000162989.5 | protein_coding | KCNJ3 | No | No | 3760 | D2X9V0 D2XBF0 P48549 |
| TVIS44044467 | HTLV-1 | ENSG00000162989.5 | protein_coding | KCNJ3 | No | No | 3760 | D2X9V0 D2XBF0 P48549 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNJ3 |
|---|---|
| DrugBank ID | DB01159 |
| Drug Name | Halothane |
| Target ID | BE0001028 |
| UniProt ID | P48549 |
| Regulation Type | inhibitor |
| PubMed IDs | 11455015; 11465552; 15175324 |
| Citations | Weigl LG, Schreibmayer W: G protein-gated inwardly rectifying potassium channels are targets for volatile anesthetics. Mol Pharmacol. 2001 Aug;60(2):282-9.@@Yamakura T, Lewohl JM, Harris RA: Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels. Anesthesiology. 2001 Jul;95(1):144-53.@@Milovic S, Steinecker-Frohnwieser B, Schreibmayer W, Weigl LG: The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus. J Biol Chem. 2004 Aug 13;279(33):34240-9. Epub 2004 Jun 2. |
| Groups | Approved; Vet_approved |
| Direct Classification | Organofluorides |
| SMILES | [H]C(Cl)(Br)C(F)(F)F |
| Pathways | |
| PharmGKB | PA449845 |
| ChEMBL | CHEMBL931 |
