| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44043957 | HTLV-1 | ENSG00000116984.15 | protein_coding | MTR | No | No | 4548 | Q99707 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MTR |
|---|---|
| DrugBank ID | DB00134 |
| Drug Name | Methionine |
| Target ID | BE0000734 |
| UniProt ID | Q99707 |
| Regulation Type | product of |
| PubMed IDs | 16618098; 16788729; 17052662; 17222188; 17615995 |
| Citations | Taurog RE, Matthews RG: Activation of methyltetrahydrofolate by cobalamin-independent methionine synthase. Biochemistry. 2006 Apr 25;45(16):5092-102.@@Hughes JA: In vivo hydrolysis of S-adenosyl-L-methionine in Escherichia coli increases export of 5-methylthioribose. Can J Microbiol. 2006 Jun;52(6):599-602.@@Reynolds E: Vitamin B12, folic acid, and the nervous system. Lancet Neurol. 2006 Nov;5(11):949-60.@@Banks EC, Doughty SW, Toms SM, Wheelhouse RT, Nicolaou A: Inhibition of cobalamin-dependent methionine synthase by substituted benzo-fused heterocycles. FEBS J. 2007 Jan;274(1):287-99.@@Yamada K, Kawata T, Wada M, Mori K, Tamai H, Tanaka N, Tadokoro T, Tobimatsu T, Toraya T, Maekawa A: Testicular injury to rats fed on soybean protein-based vitamin B12-deficient diet can be reduced by methionine supplementation. J Nutr Sci Vitaminol (Tokyo). 2007 Apr;53(2):95-101. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Methionine and derivatives |
| SMILES | CSCC[C@H](N)C(O)=O |
| Pathways | Demeclocycline Action Pathway; Spermidine and Spermine Biosynthesis; Lincomycin Action Pathway; Gentamicin Action Pathway; Josamycin Action Pathway; Methionine Adenosyltransferase Deficiency; Methacycline Action Pathway; Non-Ketotic Hyperglycinemia; Clarithromycin Action Pathway; Betaine Metabolism; Paromomycin Action Pathway; Minocycline Action Pathway; Lymecycline Action Pathway; Glycine and Serine Metabolism; Troleandomycin Action Pathway; Amikacin Action Pathway; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Methionine Metabolism; Spectinomycin Action Pathway; Doxycycline Action Pathway; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Cystathionine beta-Synthase Deficiency; Telithromycin Action Pathway; Roxithromycin Action Pathway; Tigecycline Action Pathway; Sarcosine Oncometabolite Pathway; Sarcosinemia; Arbekacin Action Pathway; Chloramphenicol Action Pathway |
| PharmGKB | PA450423 |
| ChEMBL | CHEMBL42336 |
