Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10053111HBVENSG00000010322.16protein_codingNISCHNoNo11188Q9Y2I1
TVIS10041111HBVENSG00000010322.16protein_codingNISCHNoNo11188Q9Y2I1
TVIS30008344HIVENSG00000010322.16protein_codingNISCHNoNo11188Q9Y2I1
TVIS30057445HIVENSG00000010322.16protein_codingNISCHNoNo11188Q9Y2I1
TVIS30057446HIVENSG00000010322.16protein_codingNISCHNoNo11188Q9Y2I1
TVIS30057447HIVENSG00000010322.16protein_codingNISCHNoNo11188Q9Y2I1
TVIS20016701HPVENSG00000010322.16protein_codingNISCHNoNo11188Q9Y2I1
TVIS20016702HPVENSG00000010322.16protein_codingNISCHNoNo11188Q9Y2I1
TCGA Plot Options
Drug Information
GeneNISCH
DrugBank IDDB09242
Drug NameMoxonidine
Target IDBE0003580
UniProt IDQ9Y2I1
Regulation Typeagonist
PubMed IDs8380858; 7791087
CitationsErnsberger P, Damon TH, Graff LM, Schafer SG, Christen MO: Moxonidine, a centrally acting antihypertensive agent, is a selective ligand for I1-imidazoline sites. J Pharmacol Exp Ther. 1993 Jan;264(1):172-82.@@Buccafusco JJ, Lapp CA, Westbrooks KL, Ernsberger P: Role of medullary I1-imidazoline and alpha 2-adrenergic receptors in the antihypertensive responses evoked by central administration of clonidine analogs in conscious spontaneously hypertensive rats. J Pharmacol Exp Ther. 1995 Jun;273(3):1162-71.
GroupsApproved; Investigational
Direct ClassificationHalopyrimidines
SMILESCOC1=NC(C)=NC(Cl)=C1NC1=NCCN1
Pathways
PharmGKB
ChEMBLCHEMBL19236