Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30011163HIVENSG00000171608.18protein_codingPIK3CDYesNo5293O00329
TVIS30082536HIVENSG00000171608.18protein_codingPIK3CDYesNo5293O00329
TVIS30022115HIVENSG00000171608.18protein_codingPIK3CDYesNo5293O00329
TVIS30017701HIVENSG00000171608.18protein_codingPIK3CDYesNo5293O00329
TVIS30017503HIVENSG00000171608.18protein_codingPIK3CDYesNo5293O00329
TVIS20029992HPVENSG00000171608.18protein_codingPIK3CDYesNo5293O00329
TVIS20047321HPVENSG00000171608.18protein_codingPIK3CDYesNo5293O00329
TVIS44028790HTLV-1ENSG00000171608.18protein_codingPIK3CDYesNo5293O00329
TCGA Plot Options
Drug Information
GenePIK3CD
DrugBank IDDB05552
Drug NameTG100-115
Target IDBE0002406
UniProt IDO00329
Regulation Typeinhibitor
PubMed IDs17685602
CitationsPalanki MS, Dneprovskaia E, Doukas J, Fine RM, Hood J, Kang X, Lohse D, Martin M, Noronha G, Soll RM, Wrasidlo W, Yee S, Zhu H: Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction. J Med Chem. 2007 Sep 6;50(18):4279-94. doi: 10.1021/jm051056c. Epub 2007 Aug 9.
GroupsInvestigational
Direct Classification
SMILESNC1=NC(N)=C2N=C(C3=CC=CC(O)=C3)C(=NC2=N1)C1=CC(O)=CC=C1
Pathways
PharmGKB
ChEMBLCHEMBL230011