| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10051913 | HBV | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS30007496 | HIV | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS30007497 | HIV | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS30048625 | HIV | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS30020480 | HIV | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS30017649 | HIV | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS20027059 | HPV | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS44005691 | HTLV-1 | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS44013933 | HTLV-1 | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS44024002 | HTLV-1 | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RYR1 |
|---|---|
| DrugBank ID | DB04786 |
| Drug Name | Suramin |
| Target ID | BE0000739 |
| UniProt ID | P21817 |
| Regulation Type | agonist |
| PubMed IDs | 16056233 |
| Citations | Wolner I, Kassack MU, Ullmann H, Karel A, Hohenegger M: Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676. Br J Pharmacol. 2005 Oct;146(4):525-33. |
| Groups | Investigational |
| Direct Classification | Benzanilides |
| SMILES | CC1=C(NC(=O)C2=CC(NC(=O)NC3=CC=CC(=C3)C(=O)NC3=C(C)C=CC(=C3)C(=O)NC3=C4C(C=C(C=C4S(O)(=O)=O)S(O)(=O)=O)=C(C=C3)S(O)(=O)=O)=CC=C2)C=C(C=C1)C(=O)NC1=C2C(C=C(C=C2S(O)(=O)=O)S(O)(=O)=O)=C(C=C1)S(O)(=O)=O |
| Pathways | |
| PharmGKB | PA10292 |
| ChEMBL | CHEMBL265502 |
