| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30042879 | HIV | ENSG00000129214.15 | protein_coding | SHBG | No | No | 6462 | B0FWH2 B0FWH8 B4DYU0 I3L145 P04278 |
| TVIS44036820 | HTLV-1 | ENSG00000129214.15 | protein_coding | SHBG | No | No | 6462 | B0FWH2 B0FWH8 B4DYU0 I3L145 P04278 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | SHBG |
|---|---|
| DrugBank ID | DB00367 |
| Drug Name | Levonorgestrel |
| Target ID | BE0000685 |
| UniProt ID | P04278 |
| Regulation Type | inhibitor |
| PubMed IDs | 12586319; 11521119; 9866001; 2498034 |
| Citations | Hammond GL, Abrams LS, Creasy GW, Natarajan J, Allen JG, Siiteri PK: Serum distribution of the major metabolites of norgestimate in relation to its pharmacological properties. Contraception. 2003 Feb;67(2):93-9.@@Hammond GL, Rabe T, Wagner JD: Preclinical profiles of progestins used in formulations of oral contraceptives and hormone replacement therapy. Am J Obstet Gynecol. 2001 Aug;185(2 Suppl):S24-31.@@Alvarez F, Brache V, Tejada AS, Cochon L, Faundes A: Sex hormone binding globulin and free levonorgestrel index in the first week after insertion of Norplant implants. Contraception. 1998 Oct;58(4):211-4.@@Song S, Chen JK, He ML, Fotherby K: Effect of some oral contraceptives on serum concentrations of sex hormone binding globulin and ceruloplasmin. Contraception. 1989 Apr;39(4):385-99. |
| Groups | Approved; Investigational |
| Direct Classification | Estrogens and derivatives |
| SMILES | [H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H] |
| Pathways | |
| PharmGKB | PA450218 |
| ChEMBL | CHEMBL1389 |
