| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10025044 | HBV | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
| TVIS10025757 | HBV | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
| TVIS30011167 | HIV | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
| TVIS30081362 | HIV | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
| TVIS30022237 | HIV | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
| TVIS30022238 | HIV | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
| TVIS20045298 | HPV | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
| TVIS20047422 | HPV | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
| TVIS20048225 | HPV | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
| TVIS44024369 | HTLV-1 | ENSG00000120949.15 | protein_coding | TNFRSF8 | No | No | 943 | A5D8T4 P28908 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TNFRSF8 |
|---|---|
| DrugBank ID | DB08870 |
| Drug Name | Brentuximab vedotin |
| Target ID | BE0003479 |
| UniProt ID | P28908 |
| Regulation Type | binder |
| PubMed IDs | 12714494; 33807678 |
| Citations | Francisco JA, Cerveny CG, Meyer DL, Mixan BJ, Klussman K, Chace DF, Rejniak SX, Gordon KA, DeBlanc R, Toki BE, Law CL, Doronina SO, Siegall CB, Senter PD, Wahl AF: cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity. Blood. 2003 Aug 15;102(4):1458-65. Epub 2003 Apr 24.@@Kyriakidis I, Vasileiou E, Rossig C, Roilides E, Groll AH, Tragiannidis A: Invasive Fungal Diseases in Children with Hematological Malignancies Treated with Therapies That Target Cell Surface Antigens: Monoclonal Antibodies, Immune Checkpoint Inhibitors and CAR T-Cell Therapies. J Fungi (Basel). 2021 Mar 5;7(3). pii: jof7030186. doi: 10.3390/jof7030186. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1742994 |
