Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10007554HBVENSG00000204977.10protein_codingTRIM13NoNo10206O60858
TVIS30035162HIVENSG00000204977.10protein_codingTRIM13NoNo10206O60858
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Drug Information
GeneTRIM13
DrugBank IDDB01565
Drug NameDihydromorphine
Target IDBE0001063
UniProt IDO60858
Regulation Typeagonist
PubMed IDs1654566; 2828423; 2835832; 2855368; 2985086
CitationsLiebmann C, Schnittler M, Hartrodt B, Born I, Neubert K: Structure-activity studies of novel casomorphin analogues: binding profiles towards mu 1-, mu 2- and delta -opioid receptors. Pharmazie. 1991 May;46(5):345-8.@@Maneckjee R, Archer S, Zukin RS: Characterization of a polyclonal antibody to the mu opioid receptor. J Neuroimmunol. 1988 Feb;17(3):199-208.@@Ishizuka Y, Oka T: Relation of diltiazem binding sites to opioid receptor subtypes in the guinea-pig brain. Tokai J Exp Clin Med. 1987 Mar;12(1):11-7.@@Koman A, Kolb VM, Terenius L: A naloxone-steroid hybrid azine with selective and long-acting opioid antagonism at delta receptors in vitro. Pharm Res. 1987 Apr;4(2):147-9.@@Ho CL, Hammonds RG Jr, Li CH: Opiate receptor binding profile in the rabbit cerebellum and brain membranes. Biochem Pharmacol. 1985 Apr 1;34(7):925-31.
GroupsExperimental; Illicit
Direct ClassificationMorphinans
SMILES[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])CC[C@@H]2O
PathwaysDihydromorphine Action Pathway
PharmGKB
ChEMBLCHEMBL1500