| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10007567 | HBV | ENSG00000258947.8 | protein_coding | TUBB3 | No | No | 10381 | Q13509 |
| TVIS10016139 | HBV | ENSG00000258947.8 | protein_coding | TUBB3 | No | No | 10381 | Q13509 |
| TVIS10027707 | HBV | ENSG00000258947.8 | protein_coding | TUBB3 | No | No | 10381 | Q13509 |
| TVIS44031295 | HTLV-1 | ENSG00000258947.8 | protein_coding | TUBB3 | No | No | 10381 | Q13509 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TUBB3 |
|---|---|
| DrugBank ID | DB04845 |
| Drug Name | Ixabepilone |
| Target ID | BE0001415 |
| UniProt ID | Q13509 |
| Regulation Type | inhibitor |
| PubMed IDs | 18378531; 18321240; 18945860 |
| Citations | Vahdat L: Ixabepilone: a novel antineoplastic agent with low susceptibility to multiple tumor resistance mechanisms. Oncologist. 2008 Mar;13(3):214-21. doi: 10.1634/theoncologist.2007-0167.@@Denduluri N, Swain SM: Ixabepilone for the treatment of solid tumors: a review of clinical data. Expert Opin Investig Drugs. 2008 Mar;17(3):423-35. doi: 10.1517/13543784.17.3.423 .@@Goodin S: Ixabepilone: a novel microtubule-stabilizing agent for the treatment of metastatic breast cancer. Am J Health Syst Pharm. 2008 Nov 1;65(21):2017-26. doi: 10.2146/ajhp070628. |
| Groups | Approved; Investigational |
| Direct Classification | Epothilones and analogues |
| SMILES | [H][C@]12C[C@H](NC(=O)C[C@H](O)C(C)(C)C(=O)[C@H](C)[C@@H](O)[C@@H](C)CCC[C@@]1(C)O2)C(C)=CC1=CSC(C)=N1 |
| Pathways | |
| PharmGKB | PA165958343 |
| ChEMBL | CHEMBL1201752 |
