| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30031535 | HIV | ENSG00000149554.15 | protein_coding | CHEK1 | No | Yes | 1111 | E7EPP6 O14757 |
| TVIS30031536 | HIV | ENSG00000149554.15 | protein_coding | CHEK1 | No | Yes | 1111 | E7EPP6 O14757 |
| TVIS30031537 | HIV | ENSG00000149554.15 | protein_coding | CHEK1 | No | Yes | 1111 | E7EPP6 O14757 |
| TVIS30031538 | HIV | ENSG00000149554.15 | protein_coding | CHEK1 | No | Yes | 1111 | E7EPP6 O14757 |
| TVIS20049706 | HPV | ENSG00000149554.15 | protein_coding | CHEK1 | No | Yes | 1111 | E7EPP6 O14757 |
| TVIS44008453 | HTLV-1 | ENSG00000149554.15 | protein_coding | CHEK1 | No | Yes | 1111 | E7EPP6 O14757 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHEK1 |
|---|---|
| DrugBank ID | DB12284 |
| Drug Name | LY-2608204 |
| Target ID | BE0003382 |
| UniProt ID | O14757 |
| Regulation Type | inhibitor |
| PubMed IDs | 32610557 |
| Citations | Yang CY, Liu CR, Chang IY, OuYang CN, Hsieh CH, Huang YL, Wang CI, Jan FW, Wang WL, Tsai TL, Liu H, Tseng CP, Chang YS, Wu CC, Chang KP: Cotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts. Cancers (Basel). 2020 Jun 29;12(7). pii: cancers12071726. doi: 10.3390/cancers12071726. |
| Groups | Investigational |
| Direct Classification | Phenylacetamides |
| SMILES | O=C(NC1=NC=C(SCCN2CCCC2)S1)[C@@]1(C[C@H]1C1CCCCC1)C1=CC=C(C=C1)S(=O)(=O)C1CC1 |
| Pathways | |
| PharmGKB | |
| ChEMBL |
