| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10039334 | HBV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
| TVIS10025477 | HBV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
| TVIS10017311 | HBV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
| TVIS10046139 | HBV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
| TVIS10049206 | HBV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
| TVIS30014426 | HIV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
| TVIS30067151 | HIV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
| TVIS20010234 | HPV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
| TVIS20038169 | HPV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
| TVIS20062174 | HPV | ENSG00000164742.16 | protein_coding | ADCY1 | No | No | 107 | C9J1J0 Q08828 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADCY1 |
|---|---|
| DrugBank ID | DB02587 |
| Drug Name | Colforsin |
| Target ID | BE0010179 |
| UniProt ID | O60503 |
| Regulation Type | activator |
| PubMed IDs | 12215855; 26718405; 2153444; 10969137; 17995938 |
| Citations | Uckert S, Stief CG, Lietz B, Burmester M, Jonas U, Machtens SA: Possible role of bioactive peptides in the regulation of human detrusor smooth muscle - functional effects in vitro and immunohistochemical presence. World J Urol. 2002 Sep;20(4):244-9. doi: 10.1007/s00345-002-0287-y. Epub 2002 Jul 23.@@Al-Hazza A, Linley J, Aziz Q, Hunter M, Sandle G: Upregulation of basolateral small conductance potassium channels (KCNQ1/KCNE3) in ulcerative colitis. Biochem Biophys Res Commun. 2016 Feb 5;470(2):473-478. doi: 10.1016/j.bbrc.2015.12.086. Epub 2015 Dec 21.@@Lando M, Abemayor E, Verity MA, Sidell N: Modulation of intracellular cyclic adenosine monophosphate levels and the differentiation response of human neuroblastoma cells. Cancer Res. 1990 Feb 1;50(3):722-7.@@Aiyar N, Disa J, Dang K, Pronin AN, Benovic JL, Nambi P: Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors. Eur J Pharmacol. 2000 Sep 1;403(1-2):1-7. doi: 10.1016/s0014-2999(00)00419-2.@@Monaghan TK, Mackenzie CJ, Plevin R, Lutz EM: PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases. J Neurochem. 2008 Jan;104(1):74-88. doi: 10.1111/j.1471-4159.2007.05018.x. Epub 2007 Nov 6. |
| Groups | Experimental; Investigational |
| Direct Classification | Triterpenoids |
| SMILES | [H][C@]1(O)CCC(C)(C)[C@]2([H])[C@]([H])(O)[C@]([H])(OC(C)=O)[C@@]3(C)O[C@](C)(CC(=O)[C@]3(O)[C@@]12C)C=C |
| Pathways | |
| PharmGKB | PA146096022 |
| ChEMBL | CHEMBL52606 |
