| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20027407 | HPV | ENSG00000176697.20 | protein_coding | BDNF | No | No | 627 | A0A0E3SU01 P23560 |
| TVIS44040782 | HTLV-1 | ENSG00000176697.20 | protein_coding | BDNF | No | No | 627 | A0A0E3SU01 P23560 |
| TVIS44040936 | HTLV-1 | ENSG00000176697.20 | protein_coding | BDNF | No | No | 627 | A0A0E3SU01 P23560 |
| TVIS44040935 | HTLV-1 | ENSG00000176697.20 | protein_coding | BDNF | No | No | 627 | A0A0E3SU01 P23560 |
| TVIS44046696 | HTLV-1 | ENSG00000176697.20 | protein_coding | BDNF | No | No | 627 | A0A0E3SU01 P23560 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | BDNF |
|---|---|
| DrugBank ID | DB11823 |
| Drug Name | Esketamine |
| Target ID | BE0003394 |
| UniProt ID | P23560 |
| Regulation Type | agonist |
| PubMed IDs | 29736744; 24103211; 22407616 |
| Citations | Molero P, Ramos-Quiroga JA, Martin-Santos R, Calvo-Sanchez E, Gutierrez-Rojas L, Meana JJ: Antidepressant Efficacy and Tolerability of Ketamine and Esketamine: A Critical Review. CNS Drugs. 2018 May;32(5):411-420. doi: 10.1007/s40263-018-0519-3.@@Haile CN, Murrough JW, Iosifescu DV, Chang LC, Al Jurdi RK, Foulkes A, Iqbal S, Mahoney JJ 3rd, De La Garza R 2nd, Charney DS, Newton TF, Mathew SJ: Plasma brain derived neurotrophic factor (BDNF) and response to ketamine in treatment-resistant depression. Int J Neuropsychopharmacol. 2014 Feb;17(2):331-6. doi: 10.1017/S1461145713001119. Epub 2013 Oct 8.@@Autry AE, Monteggia LM: Brain-derived neurotrophic factor and neuropsychiatric disorders. Pharmacol Rev. 2012 Apr;64(2):238-58. doi: 10.1124/pr.111.005108. Epub 2012 Mar 8. |
| Groups | Approved; Investigational |
| Direct Classification | Chlorobenzenes |
| SMILES | CN[C@@]1(CCCCC1=O)C1=CC=CC=C1Cl |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL395091 |
