| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10062353 | HBV | ENSG00000160200.18 | protein_coding | CBS | No | No | 875 | P35520 |
| TVIS10062354 | HBV | ENSG00000160200.18 | protein_coding | CBS | No | No | 875 | P35520 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CBS |
|---|---|
| DrugBank ID | DB00151 |
| Drug Name | Cysteine |
| Target ID | BE0000323 |
| UniProt ID | P35520 |
| Regulation Type | |
| PubMed IDs | 16428267; 17377202; 17488480; 16781459; 15671155 |
| Citations | Zhang H, Zhi L, Moore PK, Bhatia M: Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1193-201. Epub 2006 Jan 20.@@Lowicka E, Beltowski J: Hydrogen sulfide (H2S) - the third gas of interest for pharmacologists. Pharmacol Rep. 2007 Jan-Feb;59(1):4-24.@@Tamizhselvi R, Moore PK, Bhatia M: Hydrogen sulfide acts as a mediator of inflammation in acute pancreatitis: in vitro studies using isolated mouse pancreatic acinar cells. J Cell Mol Med. 2007 Mar-Apr;11(2):315-26.@@Oh GS, Pae HO, Lee BS, Kim BN, Kim JM, Kim HR, Jeon SB, Jeon WK, Chae HJ, Chung HT: Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Free Radic Biol Med. 2006 Jul 1;41(1):106-19. Epub 2006 Apr 25.@@Bhatia M, Wong FL, Fu D, Lau HY, Moochhala SM, Moore PK: Role of hydrogen sulfide in acute pancreatitis and associated lung injury. FASEB J. 2005 Apr;19(6):623-5. Epub 2005 Jan 25. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Cysteine and derivatives |
| SMILES | N[C@@H](CS)C(O)=O |
| Pathways | Amiloride Action Pathway; gamma-Glutamyltranspeptidase Deficiency; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Hydroflumethiazide Action Pathway; Bumetanide Action Pathway; Polythiazide Action Pathway; Ethacrynic Acid Action Pathway; Cyclothiazide Action Pathway; Trichlormethiazide Action Pathway; gamma-Glutamyltransferase Deficiency; Methionine Adenosyltransferase Deficiency; Glutamate Metabolism; Chlorothiazide Action Pathway; Pantothenate and CoA Biosynthesis; Non-Ketotic Hyperglycinemia; 2-Hydroxyglutric Aciduria (D and L Form); Indapamide Action Pathway; Hyperinsulinism-Hyperammonemia Syndrome; Iminoglycinuria; Taurine and Hypotaurine Metabolism; Glycine and Serine Metabolism; Chlorthalidone Action Pathway; Bendroflumethiazide Action Pathway; Methionine Metabolism; Eplerenone Action Pathway; Cystathionine beta-Synthase Deficiency; Glucose Transporter Defect (SGLT2); Spironolactone Action Pathway; Sarcosinemia; Quinethazone Action Pathway |
| PharmGKB | PA449173 |
| ChEMBL | CHEMBL863 |
