Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30016283HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS30085245HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS30085860HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS30088294HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS30082855HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS30080985HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS30086474HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS30088598HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS30083815HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS30062309HIVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TCGA Plot Options
Drug Information
GenePDE4D
DrugBank IDDB01791
Drug NamePiclamilast
Target IDBE0001287
UniProt IDQ08499
Regulation Type
PubMed IDs15765929; 10592235
CitationsBeeh KM, Beier J, Lerch C, Schulz AK, Buhl R: Effects of piclamilast, a selective phosphodiesterase-4 inhibitor, on oxidative burst of sputum cells from mild asthmatics and stable COPD patients. Lung. 2004;182(6):369-77.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct ClassificationBenzamides
SMILESCOC1=CC=C(C=C1OC1CCCC1)C(=O)NC1=C(Cl)C=NC=C1Cl
Pathways
PharmGKB
ChEMBLCHEMBL42126