Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30040174HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TVIS30040175HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TVIS30040176HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TVIS30040177HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TVIS30040178HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TVIS30040179HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TVIS30040180HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TVIS30040181HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TVIS30040182HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TVIS30040183HIVENSG00000140992.20protein_codingPDPK1NoNo5170O15530
TCGA Plot Options
Drug Information
GenePDPK1
DrugBank IDDB01946
Drug NameBisindolylmaleimide VIII
Target IDBE0001193
UniProt IDO15530
Regulation Type
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct ClassificationN-alkylindoles
SMILESCN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CN(CCCN)C2=C1C=CC=C2
Pathways
PharmGKB
ChEMBLCHEMBL269264