| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44047847 | HTLV-1 | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
| TVIS44047875 | HTLV-1 | ENSG00000196218.15 | protein_coding | RYR1 | No | No | 6261 | P21817 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RYR1 |
|---|---|
| DrugBank ID | DB09085 |
| Drug Name | Tetracaine |
| Target ID | BE0000739 |
| UniProt ID | P21817 |
| Regulation Type | modulator |
| PubMed IDs | 21624373; 20961976 |
| Citations | Laver DR, van Helden DF: Three independent mechanisms contribute to tetracaine inhibition of cardiac calcium release channels. J Mol Cell Cardiol. 2011 Sep;51(3):357-69. doi: 10.1016/j.yjmcc.2011.05.009. Epub 2011 May 19.@@Lanner JT, Georgiou DK, Joshi AD, Hamilton SL: Ryanodine receptors: structure, expression, molecular details, and function in calcium release. Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a003996. doi: 10.1101/cshperspect.a003996. Epub 2010 Oct 20. |
| Groups | Approved; Vet_approved |
| Direct Classification | Benzoic acid esters |
| SMILES | CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C |
| Pathways | |
| PharmGKB | PA451638 |
| ChEMBL | CHEMBL698 |
