| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30014102 | HIV | ENSG00000105397.16 | protein_coding | TYK2 | Yes | No | 7297 | P29597 |
| TVIS30014108 | HIV | ENSG00000105397.16 | protein_coding | TYK2 | Yes | No | 7297 | P29597 |
| TVIS30047831 | HIV | ENSG00000105397.16 | protein_coding | TYK2 | Yes | No | 7297 | P29597 |
| TVIS30047832 | HIV | ENSG00000105397.16 | protein_coding | TYK2 | Yes | No | 7297 | P29597 |
| TVIS30047833 | HIV | ENSG00000105397.16 | protein_coding | TYK2 | Yes | No | 7297 | P29597 |
| TVIS30017454 | HIV | ENSG00000105397.16 | protein_coding | TYK2 | Yes | No | 7297 | P29597 |
| TVIS20032025 | HPV | ENSG00000105397.16 | protein_coding | TYK2 | Yes | No | 7297 | P29597 |
| TVIS20022411 | HPV | ENSG00000105397.16 | protein_coding | TYK2 | Yes | No | 7297 | P29597 |
| TVIS20020749 | HPV | ENSG00000105397.16 | protein_coding | TYK2 | Yes | No | 7297 | P29597 |
Target Gene Table
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TCGA Plot Options
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Drug Information
▼
| Gene | TYK2 |
|---|---|
| DrugBank ID | DB11763 |
| Drug Name | Momelotinib |
| Target ID | BE0004146 |
| UniProt ID | P29597 |
| Regulation Type | inhibitor |
| PubMed IDs | 31450973 |
| Citations | Xu L, Feng J, Gao G, Tang H: Momelotinib for the treatment of myelofibrosis. Expert Opin Pharmacother. 2019 Nov;20(16):1943-1951. doi: 10.1080/14656566.2019.1657093. Epub 2019 Aug 26. |
| Groups | Approved; Investigational |
| Direct Classification | Phenylpyrimidines |
| SMILES | O=C(NCC#N)C1=CC=C(C=C1)C1=CC=NC(NC2=CC=C(C=C2)N2CCOCC2)=N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1078178 |
