| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10037679 | HBV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
| TVIS10031602 | HBV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
| TVIS10025527 | HBV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
| TVIS10024806 | HBV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
| TVIS10049406 | HBV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
| TVIS10049407 | HBV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
| TVIS30000179 | HIV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
| TVIS30077807 | HIV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
| TVIS30020975 | HIV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
| TVIS20031120 | HPV | ENSG00000106804.10 | protein_coding | C5 | No | No | 727 | P01031 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | C5 |
|---|---|
| DrugBank ID | DB11580 |
| Drug Name | Ravulizumab |
| Target ID | BE0000855 |
| UniProt ID | P01031 |
| Regulation Type | inhibitor |
| PubMed IDs | 34820672; 31534662 |
| Citations | Ladwig PM, Willrich MAV: Ravulizumab: Characterization and quantitation of a new C5 inhibitor using isotype specific affinity purification and high-resolution mass spectrometry. J Mass Spectrom Adv Clin Lab. 2021 Aug 12;21:10-18. doi: 10.1016/j.jmsacl.2021.08.002. eCollection 2021 Aug.@@Stern RM, Connell NT: Ravulizumab: a novel C5 inhibitor for the treatment of paroxysmal nocturnal hemoglobinuria. Ther Adv Hematol. 2019 Sep 10;10:2040620719874728. doi: 10.1177/2040620719874728. eCollection 2019. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
