| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30003726 | HIV | ENSG00000134058.12 | protein_coding | CDK7 | No | No | 1022 | A0A0S2Z3F9 D6R9G1 D6RFL0 P50613 |
| TVIS44005652 | HTLV-1 | ENSG00000134058.12 | protein_coding | CDK7 | No | No | 1022 | A0A0S2Z3F9 D6R9G1 D6RFL0 P50613 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CDK7 |
|---|---|
| DrugBank ID | DB15442 |
| Drug Name | Trilaciclib |
| Target ID | BE0001913 |
| UniProt ID | P50613 |
| Regulation Type | inhibitor |
| PubMed IDs | 26826116 |
| Citations | Bisi JE, Sorrentino JA, Roberts PJ, Tavares FX, Strum JC: Preclinical Characterization of G1T28: A Novel CDK4/6 Inhibitor for Reduction of Chemotherapy-Induced Myelosuppression. Mol Cancer Ther. 2016 May;15(5):783-93. doi: 10.1158/1535-7163.MCT-15-0775. Epub 2016 Jan 29. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | CN1CCN(CC1)C1=CN=C(NC2=NC3=C(C=C4N3C3(CCCCC3)CNC4=O)C=N2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3894860 |
