| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46000200 | BKPyv | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
| TVIS10012837 | HBV | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
| TVIS10037819 | HBV | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
| TVIS10000348 | HBV | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
| TVIS10046544 | HBV | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
| TVIS10045758 | HBV | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
| TVIS10045759 | HBV | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
| TVIS10052420 | HBV | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
| TVIS30005296 | HIV | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
| TVIS30001196 | HIV | ENSG00000188641.14 | protein_coding | DPYD | No | No | 1806 | Q12882 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | DPYD |
|---|---|
| DrugBank ID | DB03247 |
| Drug Name | Flavin mononucleotide |
| Target ID | BE0000960 |
| UniProt ID | Q12882 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved; Investigational |
| Direct Classification | Flavin nucleotides |
| SMILES | CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2 |
| Pathways | Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Dihydropyrimidinase Deficiency; Hyperornithinemia with Gyrate Atrophy (HOGA); Riboflavin Metabolism; Carnosinuria, Carnosinemia; MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy); Hyperprolinemia Type II; Pantothenate and CoA Biosynthesis; beta-Ureidopropionase Deficiency; Hypophosphatasia; L-Arginine:Glycine Amidinotransferase Deficiency; Vitamin B6 Metabolism; Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]; Doxorubicin Metabolism Pathway; UMP Synthase Deficiency (Orotic Aciduria); Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Prolidase Deficiency (PD); Pyrimidine Metabolism; Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Ornithine Aminotransferase Deficiency (OAT Deficiency); beta-Alanine Metabolism; Hyperprolinemia Type I; Nitric Oxide Signaling Pathway; Arginine and Proline Metabolism; GABA-Transaminase Deficiency; Ureidopropionase Deficiency; Prolinemia Type II |
| PharmGKB | |
| ChEMBL | CHEMBL1201794 |
