| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10057431 | HBV | ENSG00000163106.11 | protein_coding | HPGDS | No | No | 27306 | O60760 |
| TVIS44016342 | HTLV-1 | ENSG00000163106.11 | protein_coding | HPGDS | No | No | 27306 | O60760 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HPGDS |
|---|---|
| DrugBank ID | DB07615 |
| Drug Name | Tranilast |
| Target ID | BE0001167 |
| UniProt ID | O60760 |
| Regulation Type | inhibitor |
| PubMed IDs | 10592235; 2475113 |
| Citations | Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.@@Ikai K, Ujihara M, Fujii K, Urade Y: Inhibitory effect of tranilast on prostaglandin D synthetase. Biochem Pharmacol. 1989 Aug 15;38(16):2673-6. |
| Groups | Investigational |
| Direct Classification | N-cinnamoylanthranilic acids |
| SMILES | COC1=CC=C(C=CC(=O)NC2=CC=CC=C2C(O)=O)C=C1OC |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL415324 |
