| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10007115 | HBV | ENSG00000117594.10 | protein_coding | HSD11B1 | No | No | 3290 | P28845 X5D2L1 |
| TVIS30005481 | HIV | ENSG00000117594.10 | protein_coding | HSD11B1 | No | No | 3290 | P28845 X5D2L1 |
| TVIS30076589 | HIV | ENSG00000117594.10 | protein_coding | HSD11B1 | No | No | 3290 | P28845 X5D2L1 |
| TVIS30026470 | HIV | ENSG00000117594.10 | protein_coding | HSD11B1 | No | No | 3290 | P28845 X5D2L1 |
| TVIS20025360 | HPV | ENSG00000117594.10 | protein_coding | HSD11B1 | No | No | 3290 | P28845 X5D2L1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HSD11B1 |
|---|---|
| DrugBank ID | DB04652 |
| Drug Name | Corticosterone |
| Target ID | BE0000329 |
| UniProt ID | P28845 |
| Regulation Type | substrate |
| PubMed IDs | 10592235; 11755176 |
| Citations | Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.@@Pacha J, Lisa V, Miksik I: Effect of cellular differentiation on 11beta-hydroxysteroid dehydrogenase activity in the intestine. Steroids. 2002 Feb;67(2):119-26. doi: 10.1016/s0039-128x(01)00143-x. |
| Groups | Experimental |
| Direct Classification | 21-hydroxysteroids |
| SMILES | [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@]([H])(O)C[C@]12C)C(=O)CO |
| Pathways | Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency; Apparent Mineralocorticoid Excess Syndrome; Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH; 3-beta-Hydroxysteroid Dehydrogenase Deficiency; Corticosterone Methyl Oxidase I Deficiency (CMO I); 11-beta-Hydroxylase Deficiency (CYP11B1); Steroidogenesis; Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia Due to 17 alpha-Hydroxylase Deficiency; 17-alpha-Hydroxylase Deficiency (CYP17); Corticosterone Methyl Oxidase II Deficiency (CMO II); 21-Hydroxylase Deficiency (CYP21) |
| PharmGKB | |
| ChEMBL | CHEMBL110739 |
