| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10013972 | HBV | ENSG00000069535.14 | protein_coding | MAOB | No | No | 4129 | P27338 |
| TVIS20025210 | HPV | ENSG00000069535.14 | protein_coding | MAOB | No | No | 4129 | P27338 |
| TVIS20068158 | HPV | ENSG00000069535.14 | protein_coding | MAOB | No | No | 4129 | P27338 |
| TVIS20064192 | HPV | ENSG00000069535.14 | protein_coding | MAOB | No | No | 4129 | P27338 |
| TVIS20020700 | HPV | ENSG00000069535.14 | protein_coding | MAOB | No | No | 4129 | P27338 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MAOB |
|---|---|
| DrugBank ID | DB00909 |
| Drug Name | Zonisamide |
| Target ID | BE0002196 |
| UniProt ID | P27338 |
| Regulation Type | inhibitor |
| PubMed IDs | 19948168; 14965331; 11755227; 8991786; 20502722; 7856330; 18782051 |
| Citations | Sonsalla PK, Wong LY, Winnik B, Buckley B: The antiepileptic drug zonisamide inhibits MAO-B and attenuates MPTP toxicity in mice: clinical relevance. Exp Neurol. 2010 Feb;221(2):329-34. doi: 10.1016/j.expneurol.2009.11.018. Epub 2009 Dec 4.@@Murata M: Novel therapeutic effects of the anti-convulsant, zonisamide, on Parkinson's disease. Curr Pharm Des. 2004;10(6):687-93.@@Murata M, Horiuchi E, Kanazawa I: Zonisamide has beneficial effects on Parkinson's disease patients. Neurosci Res. 2001 Dec;41(4):397-9.@@Okada M, Kaneko S, Hirano T, Mizuno K, Kondo T, Otani K, Fukushima Y: Effects of zonisamide on dopaminergic system. Epilepsy Res. 1995 Nov;22(3):193-205.@@Murata M: Zonisamide: a new drug for Parkinson's disease. Drugs Today (Barc). 2010 Apr;46(4):251-8. doi: 10.1358/dot.2010.46.4.1490077.@@Okada M: [Effects of carbamazepine and zonisamide on dopaminergic system in rat striatum and hippocampus]. Nihon Shinkei Seishin Yakurigaku Zasshi. 1994 Oct;14(5):337-54.@@Farooq MU, Moore PW, Bhatt A, Aburashed R, Kassab MY: Therapeutic role of zonisamide in neuropsychiatric disorders. Mini Rev Med Chem. 2008 Sep;8(10):968-75. |
| Groups | Approved; Investigational |
| Direct Classification | Benzisoxazoles |
| SMILES | NS(=O)(=O)CC1=NOC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA451978 |
| ChEMBL | CHEMBL750 |
